Create a folder named 01_Disable_Adobe_Update

In 01_Disable_Adobe_Update create 3 folders:
_Inno
_Intunewin
Install

Download PSAppDeployToolkit and extract

Copy the Toolkit content to Install

Create a Disable_Adobe_Update.ps1 file and save in install\files folder

Edit in the 01_Disable_Adobe_Update\Install the Deploy-Application.ps1 file

Line: 64 to 76
Add # on line 120
Add # on line 123
Add # on line 160
Add # on line 163
Add below line 140 the script.

If you want to delete the shortcut on the desktop add on line 152

Making Disable_Adobe_Update.exe

Download Inno Setup and install the software

Create in Notepad++ a file Disable_Adobe_Update.iss and save to 01_Disable_Adobe_Update\_Inno

Copy and paste the below code.

Open the file with Inno Setup Compiler and generate a App id on line 8

Press the play button or F9 on your keyboard.
The .exe is in folder 01_Disable_Adobe_Update_Intunewin \Disable_Adobe_Update.exe

Making Disable_Adobe_Update.intunewin

Create a install.cmd, unistall.cmd and unistall.ps1 file and save in 01_Disable_Adobe_Update_Intunewin folder

Install.cmd

Unistall.cmd

Uninstall.ps1

Download IntuneWinAppUtil.exe

Open cmd with admin rights and go to IntuneWinAppUtil.exe

Upload Disable_Adobe_Update.intunewin

https://portal.azure.com/#blade/Microsoft_Intune_Apps/MainMenu/1/selectedMenuItem/Overview

Microsoft Intune > Client apps > Apps
App type: Windows app (Win32)
Name: Disable_Adobe_Update
Description: Disable_Adobe_Update
Pubisher: .
Category: Computer management
Display this as a featured app in the Company Portal: Yes or No
Upload a logo
Wait for complete upload
Install command: Install.cmd
Unistall command: Unistall.cmd
Install behavior: System
Operating system architecture: 64-bit
Minimum operating system: Windows 10 1607
Detection rules>
Rule type: File
Path: C:\Program Files (x86)\
File or folder: Disable_Adobe_Update
Detection method: File or folder exists
Associated with a 32-bit app on 64-bit clients: Yes

Assign a group in Assignments

You can set the Adobe Acrobat Reader DC as a Dependencies
Intune installs the reader first and then the Disable_Adobe_Update.exe